Indication

XGEVA® is a prescription medicine used to prevent fracture, spinal cord compression, or the need for radiation or surgery to bone in patients with multiple myeloma and in patients with bone metastases from solid tumors.

XGEVA® is a prescription medicine used to prevent fracture, spinal cord compression, or the need for radiation or surgery to bone in patients(see more)

XGEVA® is a prescription medicine used to prevent fracture, spinal cord compression, or the need for radiation or surgery to bone in patients with multiple myeloma and in patients with bone metastases from solid tumors.

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Getting started on XGEVA®—dosage and injection administration

Getting started on XGEVA®—dosage and injection administration

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A convenient shot every 4 weeks

It is important to follow this XGEVA® dosage schedule for the best chance of preventing serious bone problems.*

Your doctor will need to test your blood calcium levels before you start and while you are taking XGEVA®.

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XGEVA® is not cleared from your body by the kidneys

There’s no need to adjust your dose if you have lower kidney function. If your kidney function is not normal, your risk of seriously low blood calcium levels increases.

*Serious bone problems are defined as broken bones (fractures), the need for surgery to bones, the need for radiation treatments to the bone, and spinal cord compression.

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What to expect when starting XGEVA®

Before, during, and after your first shot of XGEVA®, feeling prepared can help.

Before, during, and after your first shot of XGEVA®, feeling prepared can help.

Click on the tabs for more information.

Tap on the tabs for more information.

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Calcium level check

Your doctor will test your blood calcium levels, which must be regular in order to start treatment. Your doctor will correct calcium levels if they are too low.

Learn why blood calcium levels are important here.

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Pregnancy test

Your doctor will check if you are pregnant before starting XGEVA®. Women should use highly effective birth control when taking XGEVA®. Birth control should be taken for at least 5 months after your last dose of XGEVA®.

Tell your doctor if you are pregnant, are planning a pregnancy, think you are pregnant, or are breastfeeding.

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Dental evaluation

Inform your oncologist of any dental work or if you’re having tooth pain. In clinical studies, osteonecrosis of the jaw (ONJ) was reported in some people taking XGEVA®, which can be serious. Learn more about ONJ here.

It’s important to visit your dentist as often as they recommend. Let your dentist know that you are taking XGEVA®.

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What to wear

When choosing what to wear to your appointment, opt for comfortable, loose-fitting clothes. This can make it easier for you, as well as the healthcare team member giving the shot.

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The shot

Your doctor will choose where to give the shot. It is given under the skin and does not involve an infusion through the vein.

The area will first be sterilized with rubbing alcohol. After the shot, this area will be sterilized again and covered with some cotton and a bandage.

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Set up routine appointments

Talk to your doctor in advance about setting up an appointment for once every 4 weeks. This will help you to get the most benefit from XGEVA®. Use this tracker to help.

If you have missed a dose, it is important to talk to your doctor about getting back on track with XGEVA®. Find more tips for staying on track—scroll down!

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Take XGEVA® as prescribed

Even if you don’t have symptoms, it is important to be consistent with your shots to give yourself the best chance of getting the kind of results seen in clinical studies.

To see how XGEVA® worked in clinical studies, click here.

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Take calcium and vitamin D supplements for extra prevention

Continue taking these supplements at the dose prescribed by your doctor to help prevent low calcium levels in the blood.

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Stay on track with your treatment

Sticking to your treatment recommendations helps give you the best chance of preventing serious bone problems

Stay on track with XGEVA® by using these tips:

  • Schedule appointments for every 4 weeks in advance
  • Record appointments in your calendar or use this appointment tracker
  • Ask family or friends for help getting to your doctor’s office
  • Write down questions to ask your doctor before appointments
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Use a treatment journal to help you!

Includes key information about XGEVA® and caring for your bones, along with tips and personal tracking tools.

Get yours FREE when you sign up for XGEVA® Cares.

patient-journal-mockup-a

Use a treatment journal to help you!

Includes key information about XGEVA® and caring for your bones, along with tips and personal tracking tools.

Get yours FREE when you sign up for XGEVA® Cares.

Maintain a healthy mouth

Good dental health is important while taking XGEVA® because of the risk of osteonecrosis of the jaw, or ONJ. Follow these suggestions from the American Dental Association (ADA) to keep your mouth healthy:

  • Brush twice daily
  • Rinse with fluoride
  • Replace toothbrush every 3-4 months
  • Floss regularly
  • Clean dentures daily
  • Visit your dentist regularly
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Hear the real-life stories of people who chose XGEVA®—people just like you.

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Hear patient stories