Frequently Asked Questions

XGEVA^® is a type of prescription medicine called a bone-targeting medicine. More Information

XGEVA^® is used to help prevent fractures and other serious bone problems in people with multiple myeloma and in people with solid tumors that have spread to their bones. More Information

XGEVA^® is not chemotherapy or any other type of treatment for your cancer. It is used in people whose bones are weakened due to their cancer. More about XGEVA^®

XGEVA^® (denosumab) is not the same as Prolia^® (denosumab). XGEVA^® and Prolia^® contain the same medicine but they are used to treat different types of medical conditions. More Information

If you have a type of solid tumor, such as breast or prostate cancer, that has spread to your bones, or if you have multiple myeloma, your bones may be weakened due to your cancer. XGEVA^® can help prevent fractures and three other serious bone problems. More Information

XGEVA^® works to slow the breakdown of bone. See this picture to learn more

XGEVA^® is a shot given under your skin and dosed every 4 weeks. It is not given as an infusion in your vein. Learn what to expect

In people with solid tumors (such as breast or prostate) that has spread to the bone, the most common side effects were: tiredness/weakness, low phosphate levels in the blood, and nausea.

In multiple myeloma, the most common side effects were: diarrhea, nausea, low red blood cells, low platelets and calcium in the blood, back pain, swelling of the lower legs or hands, infection in the upper respiratory tract, rash, and headache.

Other serious side effects are possible with XGEVA^®. These include osteonecrosis of the jaw (ONJ), hypocalcemia, thigh bone fractures, and an increased risk of broken bones in the spine after stopping XGEVA^®. More information

Osteonecrosis (os•tee•oh•neh•CROW•sis) of the jaw, or ONJ, is a serious condition that may happen in some people who take XGEVA^®. Learn about symptoms and risks here

Caring for someone who has cancer can be challenging. Learn about how you can support them, and yourself, while they are taking XGEVA^®. Find tips and support groups

The list price for XGEVA^® is $3,194.43 per dose. However, the actual cost to you will vary; most patients do not pay this price. So it's important to contact your insurance provider. For eligible commercially insured patients you may pay as little as $5 per month for XGEVA^®. Learn about AMGEN FIRST STEP™

You may qualify for assistance with paying for your XGEVA^®, no matter what type of insurance coverage you have, or even if you do not have insurance. There are programs that may be able to help you pay for XGEVA^®. More information

Bone metastases, called “bone mets,” are when cancer cells from solid tumors spread from the original tumor, such as in the breast or prostate, to the bone. Bone mets can cause fractures and other serious bone problems. Learn about how bone mets put bones at risk

Multiple myeloma can cause “weak spots’’ called lesions in your bones. This is common and can cause fractures and other serious bone problems. More information