INDICATION

XGEVA® is a prescription medicine used to prevent fracture, spinal cord compression, or the need for radiation or surgery to bone in patients with multiple myeloma and in patients with bone metastases from solid tumors.

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Understanding Bone Lesions from Multiple Myeloma

 

Bone lesions weaken bone

Multiple myeloma can cause “weak spots”—also called lesions (pronounced LEE•shuns)—in your bones. This can lead to serious bone problems* like fractures, the need for surgery to bones, the need for radiation treatments to the bones, and spinal cord compression.1-3

How bone lesions from multiple myeloma happen

Usually, the body is constantly breaking down and rebuilding bone. This helps keep bones strong.4,5

With multiple myeloma, the breaking down and rebuilding of bones are not balanced due to abnormal signals from cancer cells.1,4

Over time, this can cause weak spots in the bones and can lead to serious bone problems.1,4

Serious bone problems are defined as:

 

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