Access to XGEVA®

XGEVA® prescription injection cost assistance

XGEVA® (denosumab) cost assistance XGEVA® (denosumab) cost assistanceBecause access to your prescribed medication is important, Amgen is committed to helping you get access to XGEVA®, whether or not you have health coverage.

Commercial insurance

  • If you have commercial insurance, you may be eligible for the XGEVA FIRST STEP™ Program, which can help reduce your out-of-pocket costs

Medicare or Medicaid

  • If you're covered by Medicare or Medicaid, and need assistance with out-of-pocket costs for your prescribed medicine, Amgen can refer you to Independent Co-pay Foundations
    • - Patient Access Network Foundation
    • - Patient Advocate Foundation Co-pay Relief
    • - Healthwell Foundation

Uninsured or underinsured patients

  • If you are uninsured or underinsured, The Safety Net Foundation may be able to help you pay for your medications*
  • The Safety Net Foundation is a nonprofit patient assistance program that provides Amgen products at no cost to qualifying patients with no or limited drug coverage who meet income eligibility requirements
  • Call 1-888-SN-AMGEN (1-888-762-6436)

*Amgen provides donations to various nonprofit independent entities but has no influence over the distribution of the funds.

XGEVA® Cost Assistance

Different coverage. Same commitment.

XGEVA FIRST STEPTM Program

XGEVA® Co-Pay Coupon Card XGEVA® Co-Pay Coupon Card The XGEVA FIRST STEPTM Program may help eligible* commercially insured patients meet their deductible, co-insurance, and co-payment.

  • No out-of pocket cost for the first dose
  • No income eligibility requirement
  • For subsequent doses, Amgen will pay the out-of-pocket amount in excess of $25 per dose, up to $10,000 in assistance per calendar year*

Contact XGEVA FIRST STEPTM Program at 1-888-65-STEP1 or AmgenFIRSTSTEP.com for full program requirements and limitations.

*Eligibility Criteria: Patient must be prescribed XGEVA®. Patient must have private commercial health insurance that covers medication costs for XGEVA®. Patient must not be a participant in any federal-, state-, or government-funded healthcare program such as Medicare, Medicare Advantage, Medicare Part D, Medicaid, Medigap, Veterans Affairs (VA), the Department of Defense (DoD), or TRICARE. Patient may not seek reimbursement for value received from the Amgen FIRST STEPTM program from any third-party payers, including flexible spending accounts or healthcare savings accounts. If at any time patients begin receiving coverage under any federal-, state-, or government-funded healthcare program, patients will no longer be eligible to participate in the Amgen FIRST STEPTM Program and must call 1-888-65-STEP1 (1-888-657-8371) Monday through Friday, 9 am-8 pm EST, to stop participation. Restrictions may apply. Amgen reserves the right to revise or terminate this program, in whole or in part, without notice at any time. This is not health insurance. Program invalid where otherwise prohibited by law. Register before any treatment. Other restrictions apply. Amgen reserves the right to revise or terminate this program, in whole or in part, without notice at any time.
Coverage Limits: Program covers out-of-pocket medication costs for the XGEVA® only. Program does not cover any other costs related to office visit or administration of XGEVA®. No out-of-pocket for first dose; $25 out-of-pocket cost for subsequent doses; maximum benefit of $10,000 per patient per calendar year. Patient is responsible for costs above these amounts. Ongoing activation of the Amgen FIRST STEPTM card is contingent on the submission of the required Explanation of Benefits (EOB) form by the healthcare provider’s office within 45 days of use of the Amgen FIRST STEPTM card. Patients will be responsible for reimbursing the program for all amounts paid out if the EOB for the date of service is not received within 45 days.

Independent Co-pay Foundations

If you have Medicare or Medicaid, there are organizations that may be able to help. Visit the sites below to learn more. Talk to your doctor or doctor's office staff for assistance in registering for these or other independent programs.

For co-pay support or to be connected to an Independent Co-pay Foundation, visit www.amgenassistonline.com or call 1-888-4ASSIST (1-888-427-7478).

The Safety Net Foundation

If you are uninsured or underinsured, you may be eligible for assistance. Amgen Assist® can refer you to The Safety Net Foundation, which may provide XGEVA® at no cost to eligible patients.

To enroll or learn more about the Safety Net Foundation,
call 1-888-SN-AMGEN (1-888-762-6436).

Cancer Support Programs

Get the help you want and support you need

You are not alone. You have your doctor, nurse, and other members of your healthcare team supporting you, as well as a wide range of other resources available.

These third-party cancer support resources are for your information only. Amgen does not endorse and is not responsible for the content included in these resources.

For all patients with cancer:

Important Safety Information

Do not take XGEVA® if you have low blood calcium (hypocalcemia). Your low blood calcium must be treated before you receive XGEVA®. XGEVA® can significantly lower the calcium levels in your blood and some deaths have been reported. Take calcium and vitamin D as your doctor tells you to. Tell your doctor right away if you experience spasms, twitches, cramps, or stiffness in your muscles or numbness or tingling in your fingers, toes, or around your mouth.

Do not take XGEVA® if you are allergic to denosumab or any of the ingredients of XGEVA®. Serious allergic reactions have happened in people who take XGEVA®. Call your doctor or go to your nearest emergency room right away if you have any symptoms of a serious allergic reaction, including low blood pressure (hypotension); trouble breathing; throat tightness; swelling of the face, lips, or tongue, rash; itching; or hives.

What is the most important information you should know about XGEVA®?

XGEVA® contains the same medicine as Prolia® (denosumab). If you are taking XGEVA® do not take Prolia®.

Severe jaw bone problems (osteonecrosis)

  • Severe jaw bone problems may happen when you take XGEVA®. Your doctor should examine your mouth before you start, and while you are taking XGEVA®. Tell your dentist that you are taking XGEVA®. It is important for you to practice good mouth care during treatment with XGEVA®. In studies of patients with bone metastases, the rate of severe jaw problems was higher the longer they were being treated with XGEVA®.

Unusual thigh bone fracture

  • Unusual thigh bone fracture has been reported. Symptoms of a fracture include new or unusual pain in your hip, groin, or thigh.

Risk of high calcium levels in patients who are still growing

  • Patients with bones that are not fully matured are at a greater risk to develop high blood calcium levels after they stop taking XGEVA®, that can be serious.

Possible harm to your unborn baby

  • You should not become pregnant while taking XGEVA®. Tell your doctor right away if you are pregnant, plan to become pregnant, or suspect you are pregnant. XGEVA® can harm your unborn baby. Women of child bearing age should use highly effective contraception while taking XGEVA® and for at least 5 months after the last dose of XGEVA®.

Tell your doctor if you:

  • Are taking a medicine called Prolia® (denosumab) because it contains the same medicine as XGEVA®
  • Have symptoms of low blood calcium such as muscle stiffness or cramps
  • Have symptoms of severe jaw bone problems such as pain or numbness
  • Have ongoing pain or slow healing after dental surgery
  • Have symptoms of high blood calcium such as nausea, vomiting, headache, and decreased alertness
  • Are pregnant, plan to become pregnant, suspect you are pregnant, or breastfeeding

While taking XGEVA®, you should:

  • Take good care of your teeth and gums and visit a dentist as recommended
  • Tell your dentist that you are taking XGEVA®
  • Tell your doctor if you plan to have dental surgery or teeth removed
  • Women of child bearing age should use highly effective contraception while taking XGEVA® and for at least 5 months after the last dose of XGEVA®

What are the possible side effects of XGEVA®?

  • The most common side effects in patients receiving XGEVA® for the prevention of serious bone problems were tiredness/weakness, low phosphate levels in your blood, and nausea. The most common serious side effect of XGEVA® was shortness of breath.

These are not all the possible side effects of XGEVA®. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Indication and Limitation of Use

XGEVA® is a prescription medicine used to prevent fracture, spinal cord compression, or the need for radiation or surgery to bone in patients with bone metastases from solid tumors.
XGEVA® is not used to prevent these bone problems in patients with multiple myeloma.

Please see Full Prescribing Information.

Important Safety Information

Do not take XGEVA® if you have low blood calcium (hypocalcemia). Your low blood calcium must be treated before you receive XGEVA®. XGEVA® can significantly lower the calcium levels in your blood and some deaths have been reported. Take calcium and vitamin D as your doctor tells you to. Tell your doctor right away if you experience spasms, twitches, cramps, or stiffness in your muscles or numbness or tingling in your fingers, toes, or around your mouth.

Do not take XGEVA® if you are allergic to denosumab or any of the ingredients of XGEVA®. Serious allergic reactions have happened in people who take XGEVA®. Call your doctor or go to your nearest emergency room right away if you have any symptoms of a serious allergic reaction, including low blood pressure (hypotension); trouble breathing; throat tightness; swelling of the face, lips, or tongue, rash; itching; or hives.

What is the most important information you should know about XGEVA®?

XGEVA® contains the same medicine as Prolia® (denosumab). If you are taking XGEVA® do not take Prolia®.

Severe jaw bone problems (osteonecrosis)

  • Severe jaw bone problems may happen when you take XGEVA®. Your doctor should examine your mouth before you start, and while you are taking XGEVA®. Tell your dentist that you are taking XGEVA®. It is important for you to practice good mouth care during treatment with XGEVA®. In studies of patients with bone metastases, the rate of severe jaw problems was higher the longer they were being treated with XGEVA®.

Unusual thigh bone fracture

  • Unusual thigh bone fracture has been reported. Symptoms of a fracture include new or unusual pain in your hip, groin, or thigh.

Risk of high calcium levels in patients who are still growing

  • Patients with bones that are not fully matured are at a greater risk to develop high blood calcium levels after they stop taking XGEVA®, that can be serious.

Possible harm to your unborn baby

  • You should not become pregnant while taking XGEVA®. Tell your doctor right away if you are pregnant, plan to become pregnant, or suspect you are pregnant. XGEVA® can harm your unborn baby. Women of child bearing age should use highly effective contraception while taking XGEVA® and for at least 5 months after the last dose of XGEVA®.

Tell your doctor if you:

  • Are taking a medicine called Prolia® (denosumab) because it contains the same medicine as XGEVA®
  • Have symptoms of low blood calcium such as muscle stiffness or cramps
  • Have symptoms of severe jaw bone problems such as pain or numbness
  • Have ongoing pain or slow healing after dental surgery
  • Have symptoms of high blood calcium such as nausea, vomiting, headache, and decreased alertness
  • Are pregnant, plan to become pregnant, suspect you are pregnant, or breastfeeding

While taking XGEVA®, you should:

  • Take good care of your teeth and gums and visit a dentist as recommended
  • Tell your dentist that you are taking XGEVA®
  • Tell your doctor if you plan to have dental surgery or teeth removed
  • Women of child bearing age should use highly effective contraception while taking XGEVA® and for at least 5 months after the last dose of XGEVA®

What are the possible side effects of XGEVA®?

  • The most common side effects in patients receiving XGEVA® for the prevention of serious bone problems were tiredness/weakness, low phosphate levels in your blood, and nausea. The most common serious side effect of XGEVA® was shortness of breath.

These are not all the possible side effects of XGEVA®. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Indication and Limitation of Use

XGEVA® is a prescription medicine used to prevent fracture, spinal cord compression, or the need for radiation or surgery to bone in patients with bone metastases from solid tumors.
XGEVA® is not used to prevent these bone problems in patients with multiple myeloma.

Please see Full Prescribing Information.

Reference

  1. Data on file, Amgen.